Retinal Tissue Bioengineering, Materials and Methods for the Treatment of Glaucoma.

Glaucoma, a characteristic type of optic nerve degeneration in the posterior pole of the eye, is a common cause of irreversible vision loss and the second leading cause of blindness worldwide.

As an optic neuropathy, glaucoma is identified by increasing degeneration of retinal ganglion cells (RGCs), with consequential vision loss. Current treatments only postpone the development of retinal degeneration, and there are as yet no treatments available for this disability.

Recent studies have shown that replacing lost or damaged RGCs with healthy RGCs or RGC precursors, supported by appropriately designed bio-material scaffolds, could facilitate the development and enhancement of connections to ganglion cells and optic nerve axons. The consequence may be an improved retinal regeneration.

This technique could also offer the possibility for retinal regeneration in treating other forms of optic nerve ailments through RGC replacement.In this brief review, we describe the innovations and recent developments in retinal regenerative medicine such as retinal organoids and gene therapy which are specific to glaucoma treatment and focus on the selection of appropriate bio-engineering principles, biomaterials and cell therapies that are presently employed in this growing research area.

iP300v
MBS5801288-INQUIRE INQUIRE Ask for price

iP300v
T41181-10mg 10mg Ask for price
Description: iP300v

iP300v
T41181-1g 1g Ask for price
Description: iP300v

iP300v
T41181-1mg 1mg Ask for price
Description: iP300v

iP300v
T41181-50mg 50mg Ask for price
Description: iP300v

iP300v
T41181-5mg 5mg Ask for price
Description: iP300v

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) rpsS Polyclonal Antibody
MBS7151955-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) rplC Polyclonal Antibody
MBS7152331-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) yscM Polyclonal Antibody
MBS7148127-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) rplD Polyclonal Antibody
MBS7161122-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) rplB Polyclonal Antibody
MBS7161285-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) rplW Polyclonal Antibody
MBS7149037-INQUIRE INQUIRE Ask for price

Mettler Electrode pH Inlab 413 IP67 - EACH
PHM0132 EACH
EUR 444.15

IP10
chm-330 5µg
EUR 60
Description: Recombinant Human IP-10 (CXCL10)

IP-10
GWB-DB453E 0.025 mg Ask for price

IP10
E8ET1704-27 100ul
EUR 275
Description: Available in various conjugation types.

IP10
E5-00014 1mg
EUR 700

IP-10 (AP)
MBS6483424-01mL 0.1mL
EUR 635

IP-10 (AP)
MBS6483424-5x01mL 5x0.1mL
EUR 2700

IP-10 (PE)
MBS6483434-01mL 0.1mL
EUR 635

IP-10 (PE)
MBS6483434-5x01mL 5x0.1mL
EUR 2700

IP10
MBS8506873-1mg 1mg
EUR 780

IP10
MBS8506873-5x1mg 5x1mg
EUR 3365

IP10
MBS8534528-01mL 0.1mL
EUR 345

IP10
MBS8534528-01mLAF405L 0.1mL(AF405L)
EUR 565

IP10
MBS8534528-01mLAF405S 0.1mL(AF405S)
EUR 565

IP10
MBS8534528-01mLAF610 0.1mL(AF610)
EUR 565

IP10
MBS8534528-01mLAF635 0.1mL(AF635)
EUR 565

IP10 His
chm-346 5µg
EUR 60
Description: Recombinant Human IP-10 (CXCL10), His Tag

IP-10 (APC)
MBS6483425-01mL 0.1mL
EUR 635

IP-10 (APC)
MBS6483425-5x01mL 5x0.1mL
EUR 2700

IP-10 (HRP)
MBS6483428-01mL 0.1mL
EUR 635

IP-10 (HRP)
MBS6483428-5x01mL 5x0.1mL
EUR 2700

rHu IP-10
AK9082-0005 5µg Ask for price

rHu IP-10
AK9082-0025 25µg Ask for price

rHu IP-10
AK9082-0100 100µg Ask for price

rHu IP-10
AK9082-1000 1mg Ask for price

Rat IP-10
RC333161 25 µg Ask for price

IP-10 (FITC)
MBS6483427-01mL 0.1mL
EUR 635

IP-10 (FITC)
MBS6483427-5x01mL 5x0.1mL
EUR 2700

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (AP)
MBS6423317-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (AP)
MBS6423317-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (APC)
MBS6423318-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (APC)
MBS6423318-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (HRP)
MBS6423321-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (HRP)
MBS6423321-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (PE)
MBS6423327-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (PE)
MBS6423327-5x01mL 5x0.1mL
EUR 4120

InLab 738-IP67 Conductivity Probe with 1.8m cable - EACH
CON0016 EACH
EUR 648

InLab 742-IP67 Conductivity Probe with 1.8m cable - EACH
CON0018 EACH
EUR 861.3

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (FITC)
MBS6423320-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (FITC)
MBS6423320-5x01mL 5x0.1mL
EUR 4120

Human IP-10
90203-A 5 µg
EUR 130
Description: Recombinant human IP-10 (also known as CXCL10) is a disulfide-linked homodimeric protein consisting of 78 amino acid residues, and migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human IP-10 mature chain was expressed in E. coli.

Human IP-10
90203-B 25 µg
EUR 205
Description: Recombinant human IP-10 (also known as CXCL10) is a disulfide-linked homodimeric protein consisting of 78 amino acid residues, and migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human IP-10 mature chain was expressed in E. coli.

human IP-10 1 x 96
M850950096 1 unit
EUR 411.32

human IP-10 2 x 96
M850950192 1 unit
EUR 564.49

human IP-10 5 x 96
M851870005 1 unit
EUR 411.21

human IP-10 10 x 96
M851870010 1 unit
EUR 564.49

Human IP-10
HC77747 25 µg Ask for price

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (Biotin)
MBS6423319-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (Biotin)
MBS6423319-5x01mL 5x0.1mL
EUR 4120

m. CXCL10/IP-10
EK0736 1×96T
EUR 599
Description: ELISA

murine IP10 1 X 96
M660120096 1 unit
EUR 840.01

murine IP10 2 X 96
M660120192 1 unit
EUR 1489.67

IP-10 (CXCL10)
MBS517100-01mg 0.1mg
EUR 445

IP-10 (CXCL10)
MBS517100-1mg 1mg
EUR 2840

IP-10 (CXCL10)
MBS517100-5x1mg 5x1mg
EUR 12515

IP-10 (Biotin)
MBS6483426-01mL 0.1mL
EUR 635

IP-10 (Biotin)
MBS6483426-5x01mL 5x0.1mL
EUR 2700

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 405)
MBS6423322-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 405)
MBS6423322-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 490)
MBS6423323-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 490)
MBS6423323-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 550)
MBS6423324-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 550)
MBS6423324-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 650)
MBS6423325-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 650)
MBS6423325-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 750)
MBS6423326-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 750)
MBS6423326-5x01mL 5x0.1mL
EUR 4120

IP10 Rabbit mAb
59349 100ul
EUR 339

IP10 Protein
abx261535-1g 1 µg
EUR 225

IP10 Protein
20-abx261535
  • Ask for price
  • Ask for price
  • Ask for price
  • 5 ug
  • 25 ug
  • 1 mg

IP10 Protein
abx261535-50g 50 µg
EUR 3550

IP10 Protein
abx261535-5g 5 µg
EUR 325

IP10 Protein
abx261556-100g 100 µg
EUR 3550

IP10 Protein
abx261556-10g 10 µg
EUR 325

IP10 Protein
20-abx261556
  • Ask for price
  • Ask for price
  • Ask for price
  • 5 ug
  • 25 ug
  • 1 mg

IP10 Protein
abx261556-2g 2 µg
EUR 225

IP10 Protein
abx261583-100g 100 µg
EUR 3550

IP10 Protein
abx261583-10g 10 µg
EUR 325

IP10 Protein
20-abx261583
  • Ask for price
  • Ask for price
  • Ask for price
  • 5 ug
  • 25 ug
  • 1 mg

IP10 Protein
abx261583-2g 2 µg
EUR 225

IP10 Protein
abx261588-100g 100 µg
EUR 3550

IP10 Protein
abx261588-10g 10 µg
EUR 325

IP10 Protein
20-abx261588
  • Ask for price
  • Ask for price
  • Ask for price
  • 5 ug
  • 25 ug
  • 1 mg

IP10 Protein
abx261588-2g 2 µg
EUR 225

IP10 Protein
abx261845-10mg 10 mg
EUR 4587.5

IP10 Protein
20-abx261845
  • Ask for price
  • Ask for price
  • Ask for price
  • 5 ug
  • 25 ug
  • 1 mg

IP10 Protein
abx261845-5mg 5 mg
EUR 325

Rat IP-10 ELISA Kit
GWB-SKR110 96 Tests Ask for price

IP10 Rabbit pAb
E2381735 100ul
EUR 225
Description: Available in various conjugation types.

I5P2 rabbit pAb
E28PT7103 100μl
EUR 255
Description: Available in various conjugation types.

IP10 Rabbit mAb
E2R381735 100ul
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

IP10 Rabbit pAb
E2120389 100ul
EUR 225
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

I5P2 rabbit pAb
E44H15657 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

IP-10/ Rat IP- 10 ELISA Kit
ELA-E0371r 96 Tests
EUR 1063.2

IP-10 (Rat) ELISA Kit
EKA51926-5x96T 5x96T Ask for price

IP-10 (Rat) ELISA Kit
EKA51926-96T 96T
EUR 446.9

Rat IP-10 ELISA Kit
ERC0047 96Tests
EUR 625.2

Goat anti Pig IP-10
MBS225024-01mg 0.1mg
EUR 645

Goat anti Pig IP-10
MBS225024-5x01mg 5x0.1mg
EUR 2730

IP10 protein
MBS538288-0025mg 0.025mg
EUR 465

IP10 protein
MBS538288-5x0025mg 5x0.025mg
EUR 1945

IP10 protein
MBS539463-0025mg 0.025mg
EUR 465

IP10 protein
MBS539463-5x0025mg 5x0.025mg
EUR 1945

IP-10, Human, mAb 6D4
MBS584426-01mg 0.1mg
EUR 485

IP-10, Human, mAb 6D4
MBS584426-05mg 0.5mg
EUR 1695

IP-10, Human, mAb 6D4
MBS584426-1mg 1mg
EUR 2370

IP-10, Human, mAb 6D4
MBS584426-5mg 5mg
EUR 7845

Rat IP-10 (CXCL10)
MBS691814-0005mg 0.005mg
EUR 300

Rat IP-10 (CXCL10)
MBS691814-0025mg 0.025mg
EUR 450

Rat IP-10 (CXCL10)
MBS691814-5x0025mg 5x0.025mg
EUR 1725

Rat IP-10 ELISA Kit
MBS9141524-5x96Tests 5x96Tests
EUR 2615

Rat IP-10 ELISA Kit
MBS9141524-96Tests 96Tests
EUR 570

IP10 Rabbit pAb
MBS8543199-01mL 0.1mL
EUR 305

IP10 Rabbit pAb
MBS8543199-01mLAF405L 0.1mL(AF405L)
EUR 565

IP10 Rabbit pAb
MBS8543199-01mLAF405S 0.1mL(AF405S)
EUR 565

IP10 Rabbit pAb
MBS8543199-01mLAF610 0.1mL(AF610)
EUR 565

IP10 Rabbit pAb
MBS8543199-01mLAF635 0.1mL(AF635)
EUR 565

IP-10, CXCL10, rat
RC352-21 5ug
EUR 121.6

IP10 protein
30R-2531 25 ug Ask for price

IP10 protein
30R-AI087 25 ug Ask for price

I5P2 rabbit pAb
UB-GEN-11560 100 ul
EUR 200

IP10 protein
30R-2227 25 ug Ask for price

IP10 protein
30R-AI129 25 ug Ask for price

IP10 protein
30R-2530 25 ug Ask for price

Anti-Rat IP-10
RRF314 100 µg Ask for price

IP-10 Antibody
5200-100 each
EUR 464.4

IP-10 Antibody
5202-100 each
EUR 405.6

IP10 Antibody
49539 100ul
EUR 499

IP10 Antibody
49539-100ul 100ul
EUR 399.6

IP10 Antibody
49539-50ul 50ul
EUR 286.8

IP-10 Antibody
C18786-100ul 100μl
EUR 217
Description: IP-10 Rabbit Polyclonal Antibody

IP-10 Antibody
C18786-50ul 50μl
EUR 143.5
Description: IP-10 Rabbit Polyclonal Antibody

IP-10 Antibody
GWB-915352 0.5 mg Ask for price

IP10 Antibody
GWB-AA17E9 0.25 mg Ask for price

IP10 Antibody
GWB-C61241 0.025 mg Ask for price

IP-10, Antibody
GWB-BF5315 0.1 mg Ask for price

IP-10 Antibody
GWB-7580EE 0.1 mg Ask for price

IP-10, Antibody
GWB-3F616C 0.05 mg Ask for price

IP04 Antibody
E305497 100ug/200ul
EUR 275
Description: Available in various conjugation types.

Goat IP-10 ELISA Kit
EGTC0047 96Tests
EUR 625.2

IP10 Antibody
MBS5311618-01mg 0.1mg
EUR 575

IP10 Antibody
MBS5311618-5x01mg 5x0.1mg
EUR 2545

IP10 Antibody
MBS5311619-01mg 0.1mg
EUR 505

IP10 Antibody
MBS5311619-5x01mg 5x0.1mg
EUR 2235

IP10 Antibody
MBS5312722-01mg 0.1mg
EUR 965

IP10 Antibody
MBS5312722-5x01mg 5x0.1mg
EUR 4200

IP10 antibody
MBS534276-005mg 0.05mg
EUR 465

IP10 antibody
MBS534276-5x005mg 5x0.05mg
EUR 1945

IP10 antibody
MBS535766-005mg 0.05mg
EUR 465

IP10 antibody
MBS535766-5x005mg 5x0.05mg
EUR 1945

IP10 antibody
MBS535910-005mg 0.05mg
EUR 465

IP10 antibody
MBS535910-5x005mg 5x0.05mg
EUR 1945

IP-10 (MaxLight 405)
MBS6483429-01mL 0.1mL
EUR 635

IP-10 (MaxLight 405)
MBS6483429-5x01mL 5x0.1mL
EUR 2700

IP-10 (MaxLight 490)
MBS6483430-01mL 0.1mL
EUR 635

IP-10 (MaxLight 490)
MBS6483430-5x01mL 5x0.1mL
EUR 2700

IP-10 (MaxLight 550)
MBS6483431-01mL 0.1mL
EUR 635

IP-10 (MaxLight 550)
MBS6483431-5x01mL 5x0.1mL
EUR 2700

IP-10 (MaxLight 650)
MBS6483432-01mL 0.1mL
EUR 635

IP-10 (MaxLight 650)
MBS6483432-5x01mL 5x0.1mL
EUR 2700

IP-10 (MaxLight 750)
MBS6483433-01mL 0.1mL
EUR 635

IP-10 (MaxLight 750)
MBS6483433-5x01mL 5x0.1mL
EUR 2700

IP04 Antibody
MBS853657-01mg 0.1mg
EUR 345

IP04 Antibody
MBS853657-01mLAF405L 0.1mL(AF405L)
EUR 565

IP04 Antibody
MBS853657-01mLAF405S 0.1mL(AF405S)
EUR 565

IP04 Antibody
MBS853657-01mLAF610 0.1mL(AF610)
EUR 565

IP04 Antibody
MBS853657-01mLAF635 0.1mL(AF635)
EUR 565

IP10 Antibody
MBS9436282-005mL 0.05mL
EUR 325

IP10 Antibody
MBS9436282-01mL 0.1mL
EUR 435

IP10 Antibody
MBS9436282-5x01mL 5x0.1mL
EUR 1810

IP10 antibody
70R-13938 100 ug Ask for price

IP10 antibody
70R-IR011 50 ug Ask for price

IP10 antibody
70R-12295 100 ug Ask for price

IP10 antibody
70R-IR075 50 ug Ask for price

IP10 antibody
70R-IR052 50 ug Ask for price

IP10 antibody
70R-12294 100 ug Ask for price

Rat interferon-inducible protein 10-IP-10-ELISA Kit
QY-E11401 96T
EUR 400

Human IP-10 ELISA kit
CT522A 5-plate
EUR 554.4

Identification of optimal sources of cells, improving cell survival, functional integration upon transplantation, and developing techniques to deliver cells into the retinal space without provoking immune responses are the main challenges in retinal cell replacement therapies.The restoration of visual function in glaucoma patients by the RGC replacement therapies requires appropriate protocols and biotechnology methods. Tissue-engineered scaffolds, the generation of retinal organoids, and gene therapy may help to overcome some of the challenges in the generation of clinically safe RGCs.