Retinal Tissue Bioengineering, Materials and Methods for the Treatment of Glaucoma.

Glaucoma, a characteristic type of optic nerve degeneration in the posterior pole of the eye, is a common cause of irreversible vision loss and the second leading cause of blindness worldwide.

As an optic neuropathy, glaucoma is identified by increasing degeneration of retinal ganglion cells (RGCs), with consequential vision loss. Current treatments only postpone the development of retinal degeneration, and there are as yet no treatments available for this disability.

Recent studies have shown that replacing lost or damaged RGCs with healthy RGCs or RGC precursors, supported by appropriately designed bio-material scaffolds, could facilitate the development and enhancement of connections to ganglion cells and optic nerve axons. The consequence may be an improved retinal regeneration.

This technique could also offer the possibility for retinal regeneration in treating other forms of optic nerve ailments through RGC replacement.In this brief review, we describe the innovations and recent developments in retinal regenerative medicine such as retinal organoids and gene therapy which are specific to glaucoma treatment and focus on the selection of appropriate bio-engineering principles, biomaterials and cell therapies that are presently employed in this growing research area.

iP300v

T41181-10mg 10mg Ask for price
Description: iP300v

iP300v

T41181-1g 1g Ask for price
Description: iP300v

iP300v

T41181-1mg 1mg Ask for price
Description: iP300v

iP300v

T41181-50mg 50mg Ask for price
Description: iP300v

iP300v

T41181-5mg 5mg Ask for price
Description: iP300v

iP300v

MBS5801288-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) yscM Polyclonal Antibody

MBS7148127-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) rplW Polyclonal Antibody

MBS7149037-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) rplC Polyclonal Antibody

MBS7152331-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) rpsS Polyclonal Antibody

MBS7151955-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) rplD Polyclonal Antibody

MBS7161122-INQUIRE INQUIRE Ask for price

Rabbit anti-Yersinia pseudotuberculosis serotype I (strain IP32953) rplB Polyclonal Antibody

MBS7161285-INQUIRE INQUIRE Ask for price

Mettler Electrode pH Inlab 413 IP67 - EACH

PHM0132 EACH
EUR 444.15

IP10

E8ET1704-27 100ul
EUR 275
Description: Available in various conjugation types.

IP10

E5-00014 1mg
EUR 700

IP10

chm-330 5µg
EUR 60
Description: Recombinant Human IP-10 (CXCL10)

IP-10

GWB-DB453E 0.025 mg Ask for price

IP-10 (AP)

MBS6483424-01mL 0.1mL
EUR 635

IP-10 (AP)

MBS6483424-5x01mL 5x0.1mL
EUR 2700

IP-10 (PE)

MBS6483434-01mL 0.1mL
EUR 635

IP-10 (PE)

MBS6483434-5x01mL 5x0.1mL
EUR 2700

IP10

MBS8534528-01mL 0.1mL
EUR 345

IP10

MBS8534528-01mLAF405L 0.1mL(AF405L)
EUR 565

IP10

MBS8534528-01mLAF405S 0.1mL(AF405S)
EUR 565

IP10

MBS8534528-01mLAF610 0.1mL(AF610)
EUR 565

IP10

MBS8534528-01mLAF635 0.1mL(AF635)
EUR 565

IP10

MBS8506873-1mg 1mg
EUR 780

IP10

MBS8506873-5x1mg 5x1mg
EUR 3365

IP10 His

chm-346 5µg
EUR 60
Description: Recombinant Human IP-10 (CXCL10), His Tag

rHu IP-10

AK9082-0005 5µg Ask for price

rHu IP-10

AK9082-0025 25µg Ask for price

rHu IP-10

AK9082-0100 100µg Ask for price

rHu IP-10

AK9082-1000 1mg Ask for price

IP-10 (APC)

MBS6483425-01mL 0.1mL
EUR 635

IP-10 (APC)

MBS6483425-5x01mL 5x0.1mL
EUR 2700

IP-10 (HRP)

MBS6483428-01mL 0.1mL
EUR 635

IP-10 (HRP)

MBS6483428-5x01mL 5x0.1mL
EUR 2700

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (AP)

MBS6423317-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (AP)

MBS6423317-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (APC)

MBS6423318-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (APC)

MBS6423318-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (HRP)

MBS6423321-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (HRP)

MBS6423321-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (PE)

MBS6423327-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (PE)

MBS6423327-5x01mL 5x0.1mL
EUR 4120

IP-10 (FITC)

MBS6483427-01mL 0.1mL
EUR 635

IP-10 (FITC)

MBS6483427-5x01mL 5x0.1mL
EUR 2700

InLab 738-IP67 Conductivity Probe with 1.8m cable - EACH

CON0016 EACH
EUR 648

InLab 742-IP67 Conductivity Probe with 1.8m cable - EACH

CON0018 EACH
EUR 861.3

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (FITC)

MBS6423320-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (FITC)

MBS6423320-5x01mL 5x0.1mL
EUR 4120

Human IP-10

90203-A 5 µg
EUR 130
Description: Recombinant human IP-10 (also known as CXCL10) is a disulfide-linked homodimeric protein consisting of 78 amino acid residues, and migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human IP-10 mature chain was expressed in E. coli.

Human IP-10

90203-B 25 µg
EUR 205
Description: Recombinant human IP-10 (also known as CXCL10) is a disulfide-linked homodimeric protein consisting of 78 amino acid residues, and migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human IP-10 mature chain was expressed in E. coli.

human IP-10 1 x 96

M850950096 1 unit
EUR 411.32

human IP-10 2 x 96

M850950192 1 unit
EUR 564.49

human IP-10 5 x 96

M851870005 1 unit
EUR 411.21

human IP-10 10 x 96

M851870010 1 unit
EUR 564.49

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (Biotin)

MBS6423319-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (Biotin)

MBS6423319-5x01mL 5x0.1mL
EUR 4120

m. CXCL10/IP-10

EK0736 1×96T
EUR 599
Description: ELISA

murine IP10 1 X 96

M660120096 1 unit
EUR 840.01

murine IP10 2 X 96

M660120192 1 unit
EUR 1489.67

IP-10 (Biotin)

MBS6483426-01mL 0.1mL
EUR 635

IP-10 (Biotin)

MBS6483426-5x01mL 5x0.1mL
EUR 2700

IP-10 (CXCL10)

MBS517100-01mg 0.1mg
EUR 445

IP-10 (CXCL10)

MBS517100-1mg 1mg
EUR 2840

IP-10 (CXCL10)

MBS517100-5x1mg 5x1mg
EUR 12515

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 405)

MBS6423322-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 405)

MBS6423322-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 490)

MBS6423323-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 490)

MBS6423323-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 550)

MBS6423324-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 550)

MBS6423324-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 650)

MBS6423325-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 650)

MBS6423325-5x01mL 5x0.1mL
EUR 4120

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 750)

MBS6423326-01mL 0.1mL
EUR 950

ITPKB (Inositol-trisphosphate 3-kinase B, IP3K, IP3KB, PIG37, IP3K-B, IP3-3KB) (MaxLight 750)

MBS6423326-5x01mL 5x0.1mL
EUR 4120

IP10 Rabbit mAb

59349 100ul
EUR 339

IP10 protein

30R-2227 25 ug
EUR 333.6
Description: Purified recombinant Human IP10 protein

IP10 protein

30R-2530 25 ug
EUR 280
Description: Purified recombinant Human IP10 protein

IP10 protein

30R-2531 25 ug
EUR 265
Description: Purified recombinant Mouse IP10 protein

IP10 protein

30R-AI087 25 ug
EUR 312
Description: Purified recombinant Human IP10 protein

IP10 protein

30R-AI129 25 ug
EUR 312
Description: Purified recombinant Human IP10 protein

IP10 Protein

20-abx261535
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 25 ug
  • 5 ug

IP10 Protein

20-abx261556
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 25 ug
  • 5 ug

IP10 Protein

20-abx261583
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 25 ug
  • 5 ug

IP10 Protein

20-abx261588
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 25 ug
  • 5 ug

IP10 Protein

20-abx261845
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 25 ug
  • 5 ug

IP-10 (Rat) ELISA Kit

EKA51926-5x96T 5x96T Ask for price

IP-10 (Rat) ELISA Kit

EKA51926-96T 96T
EUR 446.9

IP10 Rabbit pAb

E2381735 100ul
EUR 225
Description: Available in various conjugation types.

I5P2 rabbit pAb

E28PT7103 100μl
EUR 255
Description: Available in various conjugation types.

Rat IP-10 ELISA Kit

ERC0047 96Tests
EUR 625.2

Rat IP-10 ELISA Kit

GWB-SKR110 96 Tests Ask for price

IP-10, CXCL10, rat

RC352-21 5ug
EUR 121.6

IP10 Protein

abx261535-1g 1 µg
EUR 225

IP10 Protein

abx261535-50g 50 µg
EUR 3550

IP10 Protein

abx261535-5g 5 µg
EUR 325

IP10 Protein

abx261556-100g 100 µg
EUR 3550

IP10 Protein

abx261556-10g 10 µg
EUR 325

IP10 Protein

abx261556-2g 2 µg
EUR 225

IP10 Protein

abx261583-100g 100 µg
EUR 3550

IP10 Protein

abx261583-10g 10 µg
EUR 325

IP10 Protein

abx261583-2g 2 µg
EUR 225

IP10 Protein

abx261588-100g 100 µg
EUR 3550

IP10 Protein

abx261588-10g 10 µg
EUR 325

IP10 Protein

abx261588-2g 2 µg
EUR 225

IP10 Protein

abx261845-10mg 10 mg
EUR 4587.5

IP10 Protein

abx261845-5mg 5 mg
EUR 325

IP10 Rabbit pAb

E2120389 100ul
EUR 225
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

I5P2 rabbit pAb

E44H15657 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

IP10 Rabbit mAb

E2R381735 100ul
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

IP-10, Human, mAb 6D4

MBS584426-01mg 0.1mg
EUR 485

IP-10, Human, mAb 6D4

MBS584426-05mg 0.5mg
EUR 1695

IP-10, Human, mAb 6D4

MBS584426-1mg 1mg
EUR 2370

IP-10, Human, mAb 6D4

MBS584426-5mg 5mg
EUR 7845

Rat IP-10 (CXCL10)

MBS691814-0005mg 0.005mg
EUR 300

Rat IP-10 (CXCL10)

MBS691814-0025mg 0.025mg
EUR 450

Rat IP-10 (CXCL10)

MBS691814-5x0025mg 5x0.025mg
EUR 1725

Rat IP-10 ELISA Kit

MBS9141524-5x96Tests 5x96Tests
EUR 2615

Rat IP-10 ELISA Kit

MBS9141524-96Tests 96Tests
EUR 570

IP10 Rabbit pAb

MBS8543199-01mL 0.1mL
EUR 305

IP10 Rabbit pAb

MBS8543199-01mLAF405L 0.1mL(AF405L)
EUR 565

IP10 Rabbit pAb

MBS8543199-01mLAF405S 0.1mL(AF405S)
EUR 565

IP10 Rabbit pAb

MBS8543199-01mLAF610 0.1mL(AF610)
EUR 565

IP10 Rabbit pAb

MBS8543199-01mLAF635 0.1mL(AF635)
EUR 565

Goat anti Pig IP-10

MBS225024-01mg 0.1mg
EUR 645

Goat anti Pig IP-10

MBS225024-5x01mg 5x0.1mg
EUR 2730

IP10 protein

MBS538288-0025mg 0.025mg
EUR 465

IP10 protein

MBS538288-5x0025mg 5x0.025mg
EUR 1945

IP10 protein

MBS539463-0025mg 0.025mg
EUR 465

IP10 protein

MBS539463-5x0025mg 5x0.025mg
EUR 1945

IP10 Antibody

49539 100ul
EUR 499

IP10 Antibody

49539-100ul 100ul
EUR 399.6

IP10 Antibody

49539-50ul 50ul
EUR 286.8

Goat IP-10 ELISA Kit

EGTC0047 96Tests
EUR 625.2

IP04 Antibody

E305497 100ug/200ul
EUR 275
Description: Available in various conjugation types.

IP10 antibody

70R-12294 100 ug
EUR 434
Description: Rabbit polyclonal IP10 antibody

IP10 antibody

70R-12295 100 ug
EUR 375
Description: Rabbit polyclonal IP10 antibody

IP10 antibody

70R-13938 100 ug
EUR 514
Description: Affinity purified Rabbit polyclonal IP10 antibody

IP-10 Antibody

5200-100 each
EUR 464.4

IP-10 Antibody

5202-100 each
EUR 405.6

IP10 antibody

70R-IR052 50 ug
EUR 312
Description: Affinity purified Rabbit polyclonal IP10 antibody

IP10 antibody

70R-IR075 50 ug
EUR 312
Description: Affinity purified Rabbit polyclonal IP10 antibody

IP10 antibody

70R-IR011 50 ug
EUR 312
Description: Affinity purified Rabbit polyclonal IP10 antibody

IP-10, Antibody

GWB-3F616C 0.05 mg Ask for price

IP-10 Antibody

GWB-915352 0.5 mg Ask for price

IP10 Antibody

GWB-AA17E9 0.25 mg Ask for price

IP-10 Antibody

GWB-7580EE 0.1 mg Ask for price

IP10 Antibody

GWB-C61241 0.025 mg Ask for price

IP-10, Antibody

GWB-BF5315 0.1 mg Ask for price

IP10 Antibody

R30467 100 ug
EUR 356.15
Description: C-X-C motif chemokine 10(CXCL10), also known as Interferon gamma-induced protein 10 kDa (IP10) or small-inducible cytokine B10, is a protein that in humans is encoded by the CXCL10 gene. It is a small cytokine belonging to the CXC chemokine family. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. Luster et al.(1987) reported the isolation of an interferon-inducible gene that encodes a 98-amino acid protein called IP10. The chemokine IFN-gamma-inducible protein 10, a CXC chemokine, and its receptor, CXCR3, were found to be overexpressed in lymph node cells of EAMG rats. IP10 inhibits bone marrow colony formation, has antitumor activity in vivo, is a chemoattractant for human monocytes and T cells, and promotes T cell adhesion to endothelial cells.

IP-10 (MaxLight 405)

MBS6483429-01mL 0.1mL
EUR 635

IP-10 (MaxLight 405)

MBS6483429-5x01mL 5x0.1mL
EUR 2700

IP-10 (MaxLight 490)

MBS6483430-01mL 0.1mL
EUR 635

IP-10 (MaxLight 490)

MBS6483430-5x01mL 5x0.1mL
EUR 2700

IP-10 (MaxLight 550)

MBS6483431-01mL 0.1mL
EUR 635

IP-10 (MaxLight 550)

MBS6483431-5x01mL 5x0.1mL
EUR 2700

IP-10 (MaxLight 650)

MBS6483432-01mL 0.1mL
EUR 635

IP-10 (MaxLight 650)

MBS6483432-5x01mL 5x0.1mL
EUR 2700

IP-10 (MaxLight 750)

MBS6483433-01mL 0.1mL
EUR 635

IP-10 (MaxLight 750)

MBS6483433-5x01mL 5x0.1mL
EUR 2700

IP04 Antibody

MBS853657-01mg 0.1mg
EUR 345

IP04 Antibody

MBS853657-01mLAF405L 0.1mL(AF405L)
EUR 565

IP04 Antibody

MBS853657-01mLAF405S 0.1mL(AF405S)
EUR 565

IP04 Antibody

MBS853657-01mLAF610 0.1mL(AF610)
EUR 565

IP04 Antibody

MBS853657-01mLAF635 0.1mL(AF635)
EUR 565

IP10 Antibody

MBS5311618-01mg 0.1mg
EUR 575

IP10 Antibody

MBS5311618-5x01mg 5x0.1mg
EUR 2545

IP10 Antibody

MBS5311619-01mg 0.1mg
EUR 505

IP10 Antibody

MBS5311619-5x01mg 5x0.1mg
EUR 2235

IP10 Antibody

MBS5312722-01mg 0.1mg
EUR 965

IP10 Antibody

MBS5312722-5x01mg 5x0.1mg
EUR 4200

IP10 antibody

MBS534276-005mg 0.05mg
EUR 465

IP10 antibody

MBS534276-5x005mg 5x0.05mg
EUR 1945

IP10 antibody

MBS535766-005mg 0.05mg
EUR 465

IP10 antibody

MBS535766-5x005mg 5x0.05mg
EUR 1945

IP10 antibody

MBS535910-005mg 0.05mg
EUR 465

IP10 antibody

MBS535910-5x005mg 5x0.05mg
EUR 1945

IP10 Antibody

MBS9436282-005mL 0.05mL
EUR 325

IP10 Antibody

MBS9436282-01mL 0.1mL
EUR 435

IP10 Antibody

MBS9436282-5x01mL 5x0.1mL
EUR 1810

IP-10 Antibody

C18786-100ul 100μl
EUR 217
Description: IP-10 Rabbit Polyclonal Antibody

IP-10 Antibody

C18786-50ul 50μl
EUR 143.5
Description: IP-10 Rabbit Polyclonal Antibody

Human IP-10 ELISA kit

CT522A 5-plate
EUR 554.4

IP-10 (Human) ELISA Kit

EKA51861-5x96T 5x96T Ask for price

IP-10 (Human) ELISA Kit

EKA51861-96T 96T
EUR 446.9

Human IP-10 ELISA Kit

EHC0047 96Tests
EUR 625.2

Human IP-10 (CXCL10)

GWB-2FF6E0 0.025 mg Ask for price

Sheep IP-10 ELISA Kit

ESC0047 96Tests
EUR 625.2

Identification of optimal sources of cells, improving cell survival, functional integration upon transplantation, and developing techniques to deliver cells into the retinal space without provoking immune responses are the main challenges in retinal cell replacement therapies.The restoration of visual function in glaucoma patients by the RGC replacement therapies requires appropriate protocols and biotechnology methods. Tissue-engineered scaffolds, the generation of retinal organoids, and gene therapy may help to overcome some of the challenges in the generation of clinically safe RGCs.